Nucleotide sequence of HSUR 5 RNA from herpesvirus saimiri
نویسندگان
چکیده
منابع مشابه
Noncoding RNA Herpesvirus saimiri Down - Regulation of a Host MicroRNA
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A region of the Herpesvirus saimiri genome that is not essential for replication of the virus has recently been shown to be required for its oncogenicity in New World primates. We have examined the RNAs derived from this region of the genome in permissively infected cells. Two polyadenylated RNAs, of 4.9 and 2.3 kilobases, were the major species coded for by this region of the genome. These two...
متن کاملAU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation.
AU-rich elements (AREs, usually containing repeated copies of AUUUA), when present in the 3'-untranslated regions (UTRs) of many mammalian mRNAs, confer instability on their host RNA molecules. The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (HSUR 1) also contains an AUUUA-rich sequence. Here, we report that this ARE induces rapid degradation of HSUR 1 itself and of other snRNAs...
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Transcription of Herpesvirus saimiri was characterized during the initial phases of productive infection by Northern blot analyses and hybridizations of radioactive cDNA with cloned fragments of virion L-DNA. Under conditions of immediate-early transcription, e.g., blocking of viral protein synthesis by cycloheximide, a single cytoplasmic polyadenylated viral RNA of 2.7 kilobases was found in i...
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The complete nucleotide sequence of a 179-nucleotide precursor (p5A) of 5 S ribosomal RNA from Bacillus subtilis is presented. In addition to the 116-nucleotide mature segment, the p5A molecule contains 21 additional nucleotides at its 5' end and 42 at its 3' terminus. Structural features within the p5A molecule which possibly interact with a specific maturation endonuclease (RNase M5) are ide...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1989
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/17.3.1258